An earthquake measuring 7.6 on the Richter scale jolted the town of Saravan in Iran's Southeastern Sistan and Balouchestan province on Tuesday.
The Geophysics Institute of Tehran University registered the quake at 15:14 hours local time (1044 GMT).
The epicenter of the quake was located in an area 62.03 degrees in longitude and 28.04 degrees in latitude.
In New Delhi, which is periodically shaken by temblors, the distant quake could be felt through the city, as buildings shook for more than 10 seconds and, in some areas, frightened people ran into the streets. No injuries were reported, nor were there any early reports of property damage in the Indian capital.
In Karachi, the Southern port city in Pakistan, local television broadcast images of people standing out on the streets after fleeing high-rise buildings. Tremors were felt most strongly in Southern and central parts of Pakistan.
"It seems as if the buildings will fall any minute," an unidentified man in Karachi told GEO News, a private television news network.
The only report of fatalities, however, came from the adjoining province of Baluchistan, which borders Iran, where the Human Rights Commission of Pakistan reported five deaths. Tahir Hussain, a lawyer with the human rights group, said five people had been killed in the remote town of Panjgur, 50 miles from the border with Iran.
"A wall collapsed and five people lost their lives, including three children and a woman," he said, speaking by phone from Quetta, the capital of Baluchistan.
Iran sits astride several major faults in the earth's crust, and is prone to frequent earthquakes, many of which have been devastating.
A 6.1 magnitude quake struck Bushehr province South of Iran last Tuesday killing at least 39 people and injuring 850 more as it devastated small villages. The epicenter of earthquake was located in the town of Kaki, 60 miles (96km) Southeast of Bushehr.
The nearby Bushehr nuclear plant remained undamaged.
The worst in recent times hit Bam in Southeastern Kerman province in December 2003, killing 31,000 people - about a quarter of its population - and destroying the city's ancient mud-built citadel.
The deadliest quake in the country was in June 1990 and measured 7.7 on the Richter scale. About 37,000 people were killed and more than 100,000 injured in the Northwestern provinces of Gilan and Zanjan. It devastated 27 towns and about 1,870 villages.
