Afkham's remarks came in reaction to the EP's adoption of the resolution in its Friday meeting in Brussels.
"The endorsement of a resolution regarding ties with Iran and human rights situation in the country by the EU parliament is unfounded and unacceptable," Afkham told reporters on Friday.
She reiterated that the fact that a number of hardline MPs in the EU parliament have undertaken efforts to adopt an imperative stance and continue an ambitious trend, which is rooted in ancient times' thoughts, does not comply with any political and international criterion and logic.
Afkham had also on Wednesday dismissed the draft resolution as "unrealistic and counterproductive".
In relevant remarks, Chairman of the Iranian Parliament's National Security and Foreign Policy Commission Alaeddin Boroujerdi also lashed out at the European Parliament for its resolution against the country, and described it as flagrant meddling in Iran’s internal affairs.
"The issues raised by the European Parliament Committee on Foreign Affairs are regarded as blatant intervention in Iran’s internal affairs," Boroujerdi told reporters on Thursday.
He reiterated that the European Parliament is under delusions, and said, "The draft resolution is in line with the Israeli regime’s anti-Iran bids to put the brakes on the European Union’s interactions with the incumbent Iranian administration."
Iran’s Ambassador to the UN offices in Geneva Mohsen Naziri Asl also blasted the resolution as sign of a “dangerous and concerning” course of action.